Reversible hypopigmentation of hair secondary to Vitamin B12 deficiency

Glossitis secondary to vitamin B12 deficiency anemia.

Reversible myelopathy with vitamin B12 deficiency.

Vitamin B12 deficiency causes haematological, gastrointestinal, psychiatric and neurological diseases. Subacute combined degeneration (SCD) of the spinal cord, characterised by degeneration of the lateral and posterior columns, is often found due to vitamin B12 deficiency. We report SCD occurring in a 57-year-old man who presented with a 2.5-month history of gradually progressing tingling in th...

Reversible cutaneous hyperpigmentation in vitamin B12 deficiency.

Received: 08.02.2013; Revised: 01.04.2013; Accepted: 26.04.2013 A 6 6 ye a r o l d m a l e p r e s e n t e d w i t h g e n e r a l i s e d we a k n e s s , hyperpigmentation of knuckles and decreased appetite since two months. Clinical examination revealed a bald tongue, pallor, glossitis, stomatitis, k n u c k l e p i g m e n t a t i o n , p a l m pigmentation, pigmentation of the sole (Figure...

Reversible Facial Hyperpigmentation Associated With Vitamin B12 Deficiency.

Vitamin B12 (cobalamin) deficiency is common in developing countries. Its dermatologic manifestations include hair and nail changes and glossitis. Cases of generalized hyperpigmentation associated with vitamin B12 deficiency have rarely been reported. Localized hyperpigmentation is less frequently described, affecting palms, soles, and flexural areas. We report a rare case of reversible melasma...

Vitamin B12 Deficiency

Functional vitamin B12 deficiency is a syndrome where a wide variety of symptoms in the presence of “normal” serum levels of the vitamin respond to vitamin B12 therapy. A series of patients with functional vitamin B12 deficiency are described whose presenting features were drenching night sweats and fatigue. Reliance on serum vitamin B12 levels as a diagnostic test would have obscured the cause...